Mildronate is a doping? … I am harming my health if use it?

To strengthen the heart, after the illness, my doctor prescribed Mildronate,
but now I hear that it is doping and is forbidden.
Will I not harm my health while taking this medicine?

Legal drugs

With the name of the cardioprotector Mildronate AKA Meldonium, which is available in Latvian pharmacies, and only one of them – capsules with the lowest concentration of the active ingredient of meldonium – is a non-prescription drug. The rest can only be purchased on a prescription issued by a doctor or special stores like mildronate.me or PharmaCity.me 

The World Anti-Doping Agency believes that athletes use this preparation to improve their performance. The product developer, the chairman of the Scientific Council of the Latvian Institute of Organic Synthesis, Ivars Kalvins, rejects these allegations and explains that, in the case of physical and psycho-emotional overload, meldonium prevents the formation of lactic acid and helps to prevent its negative consequences because of the excessive amount of lactic acid, sometimes dangerously affecting human health and can cause heart attack. Therefore, Mildronate is used during exercise to restore oxygen supply and consumption in the cells, activate metabolic processes! The product is used in combination therapy for the treatment of cardiovascular diseases and ischemic cerebral blood flow disorders. It does not necessarily lead to an increase in muscle mass and does not increase the body’s ability, but it is most safe to use any medication according to the doctor’s instructions and within the prescribed dose limits.

Meldonium is a structural analogue of every substance in the body’s body, gamma butyrobetaine. It has a positive effect on the body’s energy metabolism, as well as slightly activates the central nervous system.

Under increased stress, the body experiences rapid exhaustion, but when using Mildronate, the body is accustomed to withstand the load, since meldonium prevents fat burning to produce energy, to allowing more efficient use of oxygen, quick restoration of energy reserves and preparation for new loads. Assuming gamma-butyrobethene function, the active ingredient of the preparation accelerates the transfer of nerve impulses to the body and all responses also become faster and the body’s overall metabolism improves. Therefore, when using Mildronate, a tonic effect is felt – memory improves, thinking speeding up, movement agility is increased, and the body’s resistance to adverse conditions increases.

Athletes have used it for years to avoid damage to the heart muscle tissue caused by physical overload. Everyone knows that after such overload the muscles will break out the next day. This is because the cells lacked oxygen, but they had to produce energy. In the absence of an acid, the body switches to the use of glucose, but lactic acid and, consequently, muscle pain occur. Meldonium does not allow the body to switch to the painful process, and the athlete who is taking Mildronate has the opportunity to get better results than the one who is hurting, but the preparation does not help to rise higher or lift a heavier weight.

Insufficient evidence

To talk about the effect of a medicine in sports medicine, this must be demonstrated in a double-blind study. This means that neither athletes nor doctors know which participant receives the correct preparation, which is a placebo. In addition, participants in the study should be randomly selected athletes. Only if the results confirm that the medicine helps to improve the performance of athletes is a reason to consider them as doping. Mildronate has not been studied in this way. It is believed that Meldonium is listed on the basis of the subjective feelings of athletes that after using it, the feeling of well being improves.

The position of the manufacturing company “Grindeks” remains unchanged – meldonium is not doping but is widely used in the field of effective and clinical practice and Mildronate is a research-tested medicine that, as with any medicine, is safe when used according to the physician’s instructions.

Gatis Berkis, Head of the Anti-Doping Division at the National Sports Medicine Center, says that the Meldonian foot will remain in the body for 1-2 months. Therefore, despite the efforts of “Grindeks” to justify the good reputation of its pharmaceutical product, it will probably be mentioned in the near future with this name and not only the name of an athlete will mention doping. Meanwhile, the tweaking of Mariya Sharapova and Alexander Povetkin has created such an interest in the global media that Mildronate can even boast of indirect advertising.